The impact of additional Y-STR loci on resolving common haplotypes and closely related individuals☆
Received 23 January 2007; accepted 27 January 2007. published online 28 February 2007.
Abstract
Commercial Y-STR kits have permitted laboratories to go beyond the original nine minimal haplotype loci (MHL) and to discover the advantage of additional Y-STR loci in resolving common haplotypes. In an effort to examine the impact of Y-STR markers beyond the 17 loci now available in commercial kit form, new Y-STR loci are being investigated on a common set of samples representative of the major U.S. population groups. Additional Y-STRs can also increase the power of discrimination between closely related male individuals, which is important not only in forensics but also in the paternity and genetic genealogy communities.
National Institute of Standards and Technology, Biochemical Science Division, Gaithersburg, MD 20899, United States
Corresponding author at: NIST, 100 Bureau Dr., M/S 8311, Gaithersburg, MD 20899-8311, United States. Tel.: +1 301 975 5205; fax: +1 301 975 8505.
☆ These projects were funded by the National Institute of Justice through interagency agreement 2003-IJ-R-029 to the NIST Office of Law Enforcement Standards. Points of view are those of the authors and do not necessarily represent the official position or policies of the U.S. Department of Justice. Certain commercial equipment, instruments and materials are identified in order to specify experimental procedures as completely as possible. In no case does such identification imply a recommendation or endorsement by the National Institute of Standards and Technology nor does it imply that any of the materials, instruments or equipment identified are necessarily the best available for the purpose.
ABSTRACT