Forensic Science International: Genetics
Volume 1, Issue 2 , Pages 125-128 , June 2007

Relating two deep-rooted pedigrees from Central Germany by high-resolution Y-STR haplotyping

  • Manfred Kayser

      Affiliations

    • Department of Forensic Molecular Biology, Erasmus MC-University Medical Center Rotterdam, The Netherlands
    • Corresponding Author InformationCorresponding author at: Department of Forensic Molecular Biology, Erasmus MC-University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands. Tel.: +31 10 4638073; fax: +31 10 4089300.
    • ,
  • Mark Vermeulen

      Affiliations

    • Department of Forensic Molecular Biology, Erasmus MC-University Medical Center Rotterdam, The Netherlands
    • Department of Biology, Netherlands Forensic Institute, The Hague, The Netherlands
    • ,
  • Hans Knoblauch

      Affiliations

    • Vivantes Klinikum am Urban, Klinik für Psychiatrie und Psychotherapie, Berlin, Germany
    • ,
  • Herbert Schuster

      Affiliations

    • Infogen, Institut für Gesundheitsforschung und Gesundheitsmanagement, Berlin, Germany
    • ,
  • Michael Krawczak

      Affiliations

    • Institut für Medizinische Informatik und Statistik, Christian-Albrechts-Universität, Kiel, Germany
    • ,
  • Lutz Roewer

      Affiliations

    • Abteilung für Forensische Genetik, Institut für Rechtsmedizin, Charité Universitätsmedizin, Berlin, Germany

Received 29 January 2007 ,Accepted 3 February 2007.

References 

  1. Kayser M, Caglia A, Corach D, Fretwell N, Gehrig C, Graziosi G, et al. Evaluation of Y-chromosomal STRs: a multicenter study. Int. J. Legal Med. 1997;110:125–133141–149
  2. Foster EA, Jobling MA, Taylor PG, Donnelly P, de Knijff P, Mieremet R, et al. Jefferson fathered slave's last child. Nature. 1998;396:27–28
  3. Jobling MA, Gill P. Encoded evidence: DNA in forensic analysis. Nat. Rev. Genet. 2004;5:739–751
  4. Seielstad M, Bekele E, Ibrahim M, Toure A, Traore M. A view of modern human origins from Y chromosome microsatellite variation. Genome Res. 1999;9:558–567
  5. Kayser M, Krawczak M, Excoffier L, Dieltjes P, Corach D, Pascali V, et al. An extensive analysis of Y-chromosomal microsatellite haplotypes in globally dispersed human populations. Am. J. Hum. Genet. 2001;68:990–1018
  6. Jobling MA, Tyler-Smith C. The human Y chromosome: an evolutionary marker comes of age. Nat. Rev. Genet. 2003;4:598–612
  7. Hedman M, Pimenoff V, Lukka M, Sistonen P, Sajantila A. Analysis of 16 Y STR loci in the Finnish population reveals a local reduction in the diversity of male lineages. Forensic Sci. Int. 2004;142:37–43
  8. Kayser M, Brauer S, Cordaux R, Casto A, Lao O, Zhivotovsky LA, et al. Melanesian and Asian origins of Polynesians: mtDNA and Y chromosome gradients across the Pacific. Mol. Biol. Evol. 2006;23:2234–2244
  9. Kayser M, Roewer L, Hedman M, Henke L, Henke J, Brauer S, et al. Characteristics and frequency of germline mutations at microsatellite loci from the human Y chromosome, as revealed by direct observation in father/son pairs. Am. J. Hum. Genet. 2000;66:1580–1588
  10. Gusmao L, Sanchez-Diz P, Calafell F, Martin P, Alonso CA, Alvarez-Fernandez F, et al. Mutation rates at Y chromosome specific microsatellites. Hum. Mutat. 2005;26:520–528
  11. Heyer E, Puymirat J, Dieltjes P, Bakker E, de Knijff P. Estimating Y chromosome specific microsatellite mutation frequencies using deep rooting pedigrees. Hum. Mol. Genet. 1997;6:799–803
  12. Lim SK, Xue Y, Parkin EJ, Tyler-Smith C. Variation of 52 new Y-STR loci in the Y Chromosome Consortium worldwide panel of 76 diverse individuals. Int. J. Legal Med. 2007;121:124–127
  13. Walsh B. Estimating the time to the most recent common ancestor for the Y chromosome or mitochondrial DNA for a pair of individuals. Genetics. 2001;158:897–912
  14. Dupuy BM, Stenersen M, Egeland T, Olaisen B. Y-chromosomal microsatellite mutation rates: differences in mutation rate between and within loci. Hum. Mutat. 2004;117–124
  15. Willuweit S, Roewer L. On behalf of the International Forensic Y Chromosome User Group. Y Chromosome Haplotype Reference Database (YHRD): Update. Forensic Sci. Int. Genet. 2007;1:83–87

PII: S1872-4973(07)00060-9

doi: 10.1016/j.fsigen.2007.02.004

Forensic Science International: Genetics
Volume 1, Issue 2 , Pages 125-128 , June 2007

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