Forensic Science International: Genetics
Volume 2, Issue 3 , Pages 166-175, June 2008

Object-oriented Bayesian networks for paternity cases with allelic dependencies

  • Amanda B. Hepler

      Affiliations

    • Department of Statistical Science, University College London, Gower Street, London, WC1E 6BT, United Kingdom
    • Corresponding Author InformationCorresponding author. Tel: +44 20 7679 1624; fax: +44 20 7383 4703.
  • ,
  • Bruce S. Weir

      Affiliations

    • Department of Biostatistics, University of Washington, Box 357232, Seattle, WA 98195, United Kingdom

Received 29 October 2007; accepted 1 December 2007. published online 28 February 2008.

Abstract 

This study extends the current use of Bayesian networks by incorporating the effects of allelic dependencies in paternity calculations. The use of object-oriented networks greatly simplify the process of building and interpreting forensic identification models, allowing researchers to solve new, more complex problems. We explore two paternity examples: the most common scenario where DNA evidence is available from the alleged father, the mother and the child; a more complex case where DNA is not available from the alleged father, but is available from the alleged father’s brother. Object-oriented networks are built, using HUGIN, for each example which incorporate the effects of allelic dependence caused by evolutionary relatedness.

Keywords: DNA evidence, Probabilistic expert systems, Evidence interpretation, Paternity index, Avuncular index

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PII: S1872-4973(07)00403-6

doi:10.1016/j.fsigen.2007.12.003

Forensic Science International: Genetics
Volume 2, Issue 3 , Pages 166-175, June 2008