Forensic Science International: Genetics
Volume 2, Issue 4 , Pages 318-328 , September 2008

Direct comparison of post-28-cycle PCR purification and modified capillary electrophoresis methods with the 34-cycle “low copy number” (LCN) method for analysis of trace forensic DNA samples

Received 1 February 2008 ,Revised 28 March 2008 ,Accepted 9 April 2008.

References 

  1. Gill P, Whitaker JP, Flaxman C, Brown N, Buckleton J. An investigation of the rigor of interpretation rules for STRs derived from less than 100pg of DNA. Forensic Sci. Int. 2000;112:17–40
  2. Whitaker JP, Cotton EA, Gill P. A comparison of the characteristics of profiles produced with the AMPFlSTR® SGM Plus™ multiplex system for both standard and low copy number (LCN) STR DNA analysis. Forensic Sci. Int. 2001;123:215–223
  3. Gill P. Application of low copy number DNA profiling. Croat. Med. J. 2001;42:229–232
  4. Findlay I, Frazier R, Taylor A, Urquhart A. Single cell DNA fingerprinting for forensic applications. Nature. 1997;389:555–556
  5. BBC News Online, DNA test halted after Omagh case, BBC News Online, http://news.bbc.co.uk/1/hi/uk/7156051.stm, 23 December, 2007.
  6. J. Booth and agencies, Wearside Jack pleads guilty to Ripper hoax, The Times, March 20, 2006.
  7. Chris Summers, How science caught up with killer, BBC News online, http://news.bbc.co.uk/1/hi/uk/1459056.stm, 24 August, 2001.
  8. Crown Prosecution Service, Review of the use of Low Copy Number DNA analysis in current cases: CPS statement, http://www.cps.gov.uk/news/pressreleases/101_08.html, 14 January, 2008.
  9. Budowle B, Hobson DL, Smerick JB, Smith JAL. Low Copy Number—consideration and caution. In: Proceedings of the Twelfth International Symposium on Human Identification. Madison, Wisconsin: Promega Corporation; 2001;Available at: http://www.promega.com/geneticidproc/ussymp12proc/contents/budowle.pdf
  10. Prinz M, Schiffner L, Sebestyen JA, Bajda E, Tamariz J, Shaler RC, et al. Maximization of STR DNA typing success for touched objects. In: International Congress Series, vol. 1228. 2006;p. 651–653
  11. Smith PJ, Ballantyne MS, Ballantyne J. Simplified Low-Copy-Number DNA analysis by post-PCR purification. J. Forensic Sci. 2007;52:820–829
  12. Kloosterman AD, Kersbergan P. Efficacy of limits of genotyping low copy number DNA samples by multiplex PCR of STR loci. In: International Congress Series, vol. 1239. 2003;p. 795–798
  13. Cotton EA, Allsop R, Guest J, Frazier R, Koumi P, Callow IP, et al. Validation of AMPFlSTR® SGM Plus™ system for use in forensic casework. Forensic Sci. Int. 2000;112:151–161
  14. Taberlet P, Griffin S, Goossens B, Questiau S, Manceau V, Escaravage N, et al. Reliable genotyping of samples with very low DNA quantities using PCR. Nucleic Acids Res. 1996;24:1389–3194
  15. Clayton TM, Whitaker JP, Sparkes R, Gill P. Analysis and interpretation of mixed forensic stains using DNA STR profiling. Forensic Sci. Int. 1998;91:55–70
  16. Alessandrini F, Cecati M, Pesaresi M, Turchi C, Carle F, Tagliabracci A. Fingerprints as evidence for a genetic profile: morphological study on fingerprints and analysis of exogenous and individual factors affecting DNA typing. J. Forensic Sci. 2003;48:586–592
  17. Lowe A, Murray C, Whitaker J, Tully G, Gill P. The propensity of individuals to deposit DNA and secondary transfer of low level DNA from individuals to inert surfaces. Forensic Sci. Int. 2002;129:25–34
  18. Poy AL, van Oorschot RAH. Trace DNA presence, origin and transfer within a forensic biology laboratory and its potential effect on casework. J. Forensics Identification. 2006;56:558–576

PII: S1872-4973(08)00053-7

doi: 10.1016/j.fsigen.2008.04.005

Forensic Science International: Genetics
Volume 2, Issue 4 , Pages 318-328 , September 2008

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