Allele frequencies of fifteen STRs in a representative sample of the Italian population

Brisighelli, F.; Capelli, C.; Boschi, I.; Garagnani, P.; Lareu, M.V.; Pascali, V.L.; Carracedo, A.

doi:10.1016/j.fsigen.2008.05.002

« Previous Next »Forensic Science International: Genetics
Volume 3, Issue 2 , Pages e29-e30, March 2009

Allele frequencies of fifteen STRs in a representative sample of the Italian population

F. Brisighelli
- Institute of Legal Medicine, Genomics Medicine Group, University of Santiago de Compostela, Santiago de Compostela, Spain
- Forensic Genetics Laboratory, Institute of Legal Medicine, Università Cattolica del Sacro Cuore, Rome, Italy
- Corresponding author at: Institute of Legal Medicine, Genomics Medicine Group, University of Santiago de Compostela, Rúa San Francisco, s/n, 15782; Santiago de Compostela, A Coruña, España. Tel.: +34 981582327; fax: +34 981580336.
C. Capelli
- Department of Zoology, University of Oxford, Oxford, UK
I. Boschi
- Forensic Genetics Laboratory, Institute of Legal Medicine, Università Cattolica del Sacro Cuore, Rome, Italy
P. Garagnani
- Dipartimento di Biologia evoluzionistica sperimentale, Università di Bologna, Bologna, Italy
M.V. Lareu
- Institute of Legal Medicine, Genomics Medicine Group, University of Santiago de Compostela, Santiago de Compostela, Spain
V.L. Pascali
- Forensic Genetics Laboratory, Institute of Legal Medicine, Università Cattolica del Sacro Cuore, Rome, Italy
A. Carracedo
- Institute of Legal Medicine, Genomics Medicine Group, University of Santiago de Compostela, Santiago de Compostela, Spain

Received 12 February 2008; received in revised form 6 May 2008; accepted 7 May 2008. published online 24 June 2008.

Abstract

Fifteen autosomal short tandem repeat (STR) markers (D3S1358, HUMTH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta D, HUMvWA, D8S1179, HUMTPOX and FGA) were analyzed in more than 400 unrelated individuals from nine different areas of Italy. After Bonferroni correction, no evidence of population structure was identified, either by considering each population as independent or by combining populations according to their geographic origin (North, Central and South of Italy). Forensic indexes were estimated considering all samples together. Combined power of discrimination (PD) and combined power of exclusion (PE) for the 15 tested STR loci were 0.9999999997 and 0.964708775, respectively. Low genetic distances were found between our data and those previously published for other neighboring European populations.

Keywords: STRs, Population data, Powerplex 16, Italy