A case of tri-allelic pattern at locus D3S1358 on chromosome 3p21 inherited from paternal grandmother
Received 19 March 2008; received in revised form 13 May 2008; accepted 6 June 2008. published online 22 July 2008.
Abstract
We are reporting a case of tri-allelic inheritance at locus D3S1358 commonly used for genetic identification in forensic DNA testing. This case was encountered during routine paternity testing using commercial DNA profiling kits. The tri-allelic inheritance identified was probably a result of duplication at this locus, supported by the equal peak intensities and inheritance pattern from grandparent to child.