Comparison of telogen hair analyses: genRES® MPX-2SP kit versus genRES® MPX-SP1 and genRES® MPX-SP2 kits

Schmid, D.; Bayer, B.; Anslinger, K.

doi:10.1016/j.fsigen.2008.07.003

« Previous Next »Forensic Science International: Genetics
Volume 3, Issue 1 , Pages 22-26, December 2008

Comparison of telogen hair analyses: genRES^® MPX-2SP kit versus genRES^® MPX-SP1 and genRES^® MPX-SP2 kits

Institute of Legal Medicine, Ludwig-Maximilians-University of Munich, Nußbaumstr 26, 80335 Munich, Germany

Received 31 July 2007; received in revised form 17 June 2008; accepted 3 July 2008. published online 11 August 2008.

Abstract

STR investigations of telogen hair are invariably difficult due to the small amounts of nuclear DNA and its degradation products. However, in recent years there has been a considerable improvement. This study examined the suitability of a new STR kit with shortened amplicons for the investigation of hair in routine casework. This kit allows the simultaneous amplification of the eight STR-loci D3S1358, VWA, FGA, TH01, SE33, D8S1179, D18S51, and D21S11, and the sex-determining amelogenin system. It was tested against the genRES^® MPX-SP1 and genRES^® MPX-SP2 kits. The sensitivity of the new genRES^® MPX-2SP kit was demonstrated to be inferior to that of the genRES^® MPX-SP1, but almost equal to that of the genRES^® MPX-SP2 kit.

Keywords: Forensic identification, Hair roots, genRES^® MPX-SP1 and 2, genRES^® MPX-2SP