Forensic Science International: Genetics
Volume 4, Issue 2 , Pages 104-110, February 2010

Characterization of the highly discriminatory loci DYS449, DYS481, DYS518, DYS612, DYS626, DYS644 and DYS710

University of the Western Cape, Forensic DNA Laboratory, Private Bag X17, 7535 Bellville, Cape Town, South Africa

Received 29 November 2008; received in revised form 10 April 2009; accepted 29 June 2009. published online 30 July 2009.

Abstract 

During the study of genetic diversity at non-core Y-STRs in South African population groups, we identified loci with high discrimination capacity. In this study we present a detailed account of the allele diversity, allele sequence data, gene diversity, allele frequency spectrum and informativeness for assignment in the European English, Asian Indian and Xhosa population groups at loci DYS449, DYS481, DYS518, DYS612, DYS626, DYS644 and DYS710. The suitability of these loci for forensic, genealogical and evolutionary studies is discussed, and nomenclature for loci DYS518, DYS612, DYS626 and DYS644 is suggested.

Keywords: Y-STRs, Non-core Y-STRs, Xhosa, South Africa, Population genetics, Ancestry

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PII: S1872-4973(09)00101-X

doi:10.1016/j.fsigen.2009.06.011

Forensic Science International: Genetics
Volume 4, Issue 2 , Pages 104-110, February 2010