Forensic Science International: Genetics
Volume 4, Issue 3 , Pages 168-177 , April 2010

Hydrolysis of DNA and its molecular components in the dry state

  • April Marrone

      Affiliations

    • Graduate Program in Chemistry, University of Central Florida, Orlando, FL, USA
    • Department of Chemistry, University of Central Florida, Orlando, FL, USA
    • National Center for Forensic Science, Orlando, FL, USA
    • ,
  • Jack Ballantyne

      Affiliations

    • Graduate Program in Chemistry, University of Central Florida, Orlando, FL, USA
    • Department of Chemistry, University of Central Florida, Orlando, FL, USA
    • National Center for Forensic Science, Orlando, FL, USA
    • Corresponding Author InformationCorresponding author at: National Center for Forensic Science, P.O. Box 162367, Orlando, FL 32816-2367, United States. Tel.: +1 407 823 4440; fax: +1 407 823 2252.

Received 7 April 2009 ,Revised 9 August 2009 ,Accepted 11 August 2009.

References 

  1. Friedberg EC, Walker GC, Siede W, Wood RD, Schultz RA, Ellenberger T. DNA Repair and Mutagenesis. ASM Press; 2005;
  2. Ginoza W, Zimm BH. Mechanisms of inactivation of deoxyribonucleic acids by heat. Biochemistry. 1961;47:639–652
  3. Zoltewicz JA, Clark DF, Sharpless TW, Grahe G. Kinetics and mechanism of the acid-catalyzed hydrolysis of some purine nucleosides. J. Am. Chem. Soc. 1970;92:1741–1750
  4. Lindahl T. Instability and decay of the primary structure of DNA. Nature. 1993;362:715
  5. Lindahl T, Andersson A. Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid. Biochemistry. 1972;11:3618–3622
  6. Lindahl T, Karlstro O. Heat-induced depyrimidination of deoxyribonucleic acid in neutral solution. Biochemistry. 1973;12:5151–5154
  7. Lindahl T, Nyberg B. Rate of depurination of native deoxyribonucleic acid. Biochemistry. 1972;11:3610–3618
  8. Lindahl T, Nyberg B. Heat-induced deamination of cytosine residues in deoxyribonucleic acid. Biochemistry. 1974;13:3405–3410
  9. Shapiro R, Danzig M. Acidic hydrolysis of deoxycytidine and deoxyuridine derivatives. The general mechanism of deoxyribonucleoside hydrolysis. Biochemistry. 1972;11:23–29
  10. Shapiro R, Kang S. Uncatalyzed hydrolysis of deoxyuridine, thymidine, and 5-bromodeoxyuridine. Biochemistry. 1969;8:1806–1810
  11. Shapiro R, Klein RS. The deamination of cytidine and cytosine by acidic buffer solutions. Mutagenic implications. Biochemistry. 1966;5:2358–2362
  12. SantaLucia J. A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics. Proc. Natl. Acad. Sci. U.S.A. 1998;95:1460–1465
  13. Tavazzi B, Lazzarino G, Leone P, Amorini AM, Bellia F, Janson CG, et al. Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism. Clin. Biochem. 2005;38:997–1008
  14. Miller JN, Miller JC. Statistics and Chemometrics for Analytical Chemistry. Essex, England: Pearson Prentice Hall; 2000;
  15. Gross E, Arnold N, Goette J, Schwarz-Boeger U, Kiechle M. A comparison of BRCA1 mutation analysis by direct sequencing, SSCP and DHPLC. Hum. Genet. 1999;105:72–78
  16. Abbas A, Lepelley M, Lechevrel M, Sichel F. Assessment of DHPLC usefulness in the genotyping of GSTP1 exon 5 SNP: comparison to the PCR–RFLP method. J. Biochem. Biophys. Methods. 2004;59:121–126
  17. Hoogendoorn B, Owen MJ, Oefner PJ, Williams N, Austin J, O’Donovan MC. Genotyping single nucleotide polymorphisms by primer extension and high performance liquid chromatography. Hum. Genet. 1999;104:89–93
  18. Klein B, Weirich G, Brauch H. DHPLC-based germline mutation screening in the analysis of the VHL tumor suppressor geneL usefulness and limitations. Hum. Genet. 2001;108:376–384
  19. Oefner PJ. Allelic discrimination by denaturing high-performance liquid chromatography. J. Chromatogr. B. 2000;739:345–355
  20. Premstaller A, Oefner PJ. Denaturing HPLC of nucleic acids. LC–GC Eur. 2002;1:2–10
  21. Sivakumaran TA, Kucheria K, Oefner PJ. Denaturing high performance liquid chromatography in the molecular diagnosis of genetic disorders. Curr. Sci. 2003;84:291–296
  22. Greer S, Zamenhof S. Depurination of DNA by heat. J. Mol. Biol. 1962;4:123–141
  23. Tamm C, Shaprio HS, Lipshitz R, Chargaff E. Distribution density of nucleotides within a desoxyribonucleic acid chain. J. Biol. Chem. 1953;203:673–688
  24. Ullmann JS, McCarthy BJ. Alkali deamination of cytosine residues in DNA. Biochim. Biophys. Acta. 1973;294:396–404
  25. Long FA, Pritchard JG, Stafford FE. Entropies of activation and mechanism for the acid-catalyzed hydrolysis of ethylene oxide and its derivatives. J. Am. Chem. Soc. 1957;79:2362–2364
  26. Overend WG, Rees CW, Sequeira JS. Reactions at position 1 of carbohydrates. Part III. The acid-catalysed hydrolysis of glycosides. J. Chem. Soc. 1962;3429–3440
  27. Manoharan M, Ransom SC, Mazumder A, Gerlt JA. The characterization of abasic sites in DNA heteroduplexes by site specific labeling with 13C. J. Am. Chem. Soc. 1988;110:1620–1622
  28. Wilde JA, Bolton PH. Characterization of the equilibrating forms of the aldehydic abasic site in duplex DNA by 17O NMR. J. Am. Chem. Soc. 1988;111:1894–1896
  29. Chen J, Dupredeau F, Case DA. DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics. Nucleic Acids Res. 2008;36:253–262
  30. Sagi J, Guliaev AB, Singer B. 15-Mer duplexes containing an abasic site are thermodynamically more stable with adjacent purines than with pyrimidines. Biochemistry. 2001;49:3859–3868
  31. Zheng Y, Sheppard TL. Half-life and DNA strand scission products of 2-deoxyribonolactone oxidative DNA damage lesions. Chem. Res. Toxicol. 2004;17:197–207

PII: S1872-4973(09)00136-7

doi: 10.1016/j.fsigen.2009.08.007

Forensic Science International: Genetics
Volume 4, Issue 3 , Pages 168-177 , April 2010

Article Tools

* Image Usage & Resolution