Typing of 49 autosomal SNPs by SNaPshot® in the Slovenian population

Drobnič, Katja; Børsting, Claus; Rockenbauer, Eszter; Tomas, Carmen; Morling, Niels

doi:10.1016/j.fsigen.2010.01.014

« Previous Next »Forensic Science International: Genetics
Volume 4, Issue 5 , Pages e125-e127, October 2010

Typing of 49 autosomal SNPs by SNaPshot^® in the Slovenian population

Katja Drobnič
- Faculty of Criminal Justice and Security, University of Maribor, Kotnikova 8, 1000 Ljubljana, Slovenia
- Forensic Science Centre, General Police Directorate, Police, Ministry of the Interior, Slovenia
- Corresponding author at: Faculty of Criminal Justice and Security, University of Maribor, Kotnikova 8, 1000 Ljubljana, Slovenia. Tel.: +386 142 85426; fax: +386 142 84986.
Claus Børsting
- Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health Sciences, University of Copenhagen, 11 Frederik V's Vej, DK-2100 Copenhagen, Denmark
Eszter Rockenbauer
- Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health Sciences, University of Copenhagen, 11 Frederik V's Vej, DK-2100 Copenhagen, Denmark
Carmen Tomas
- Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health Sciences, University of Copenhagen, 11 Frederik V's Vej, DK-2100 Copenhagen, Denmark
Niels Morling
- Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health Sciences, University of Copenhagen, 11 Frederik V's Vej, DK-2100 Copenhagen, Denmark

Received 19 November 2009; received in revised form 19 January 2010; accepted 21 January 2010. published online 02 March 2010.

Abstract

A total of 157 unrelated individuals residing in Slovenia were typed for 49 of the autosomal single nucleotide polymorphisms (SNPs) in the SNPforID 52plex with the SNaPshot^® assay. We obtained full SNP profiles in all but one individual and perfect concordance was obtained in duplicated analyses. Allele frequencies are presented for the 49 SNPs. No deviation from HWE was observed for any SNP. F_IS and F_ST were estimated. A principal coordinate analysis performed on six populations (Slovenian, Danish, Somali, Greenland, Turkish and Chinese) showed that the Slovenian population grouped with the Danish population. The mean power of discrimination for the Slovenian population was 1.1×10⁻¹⁹, and the mean exclusion probability for trios was 99.96%.