Y-chromosome and autosomal STR diversity in four proximate settlements in Central Anatolia

Alakoc, Yesim Dogan; Gokcumen, Omer; Tug, Aysim; Gultekin, Timur; Gulec, Erksin; Schurr, Theodore G.

doi:10.1016/j.fsigen.2010.01.016

« Previous Next »Forensic Science International: Genetics
Volume 4, Issue 5 , Pages e135-e137, October 2010

Y-chromosome and autosomal STR diversity in four proximate settlements in Central Anatolia

Yesim Dogan Alakoc
- Ankara University Medical School, Department of Forensic Medicine, 06100 Cebeci, Ankara, Turkey
- These authors contributed equally to this paper.
- Corresponding author at: Biotechnology Institute, Ankara University, Tandogan-Besevler, Ankara, Turkey. Tel.: +90 3122225826.
Omer Gokcumen
- University of Pennsylvania, Department of Anthropology, Philadelphia, PA 19104-6398 USA
- These authors contributed equally to this paper.
- Current Address: Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115.
Aysim Tug
- Ankara University Medical School, Department of Forensic Medicine, 06100 Cebeci, Ankara, Turkey
Timur Gultekin
- Ankara University, Department of Anthropology, 06100 Sıhhıye, Ankara, Turkey
Erksin Gulec
- Ankara University, Department of Anthropology, 06100 Sıhhıye, Ankara, Turkey
Theodore G. Schurr
- University of Pennsylvania, Department of Anthropology, Philadelphia, PA 19104-6398 USA

Received 2 December 2008; received in revised form 26 January 2010; accepted 26 January 2010. published online 24 February 2010.

Abstract

Due to the longstanding human presence in the region and the influence of social traditions, the genetic make-up of populations currently inhabiting Turkey (Anatolia) is quite complex. To characterize the patterns of genetic diversity in rural Central Anatolian villages, we analyzed samples collected at four local settlements for variation at 17 Y-chromosome STR and 15 autosomal STR loci. The resulting data reveal considerable diversity within these settlements, as well as some structure in the paternal genetic variation, with a limited number of haplotypes being shared between the communities. These findings have important implications for forensic studies of Turkish populations.

Keywords: Forensics, DNA typing, Population genetics, Turkey, Heterozygosity, Gene diversity, Patrilineage, DYS19, DYS385a, DYS385b, DYS388, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS439, DYS448, DYS456, DYS458, DYS635, H4-YGATA, D8S1179, D21S11, D7S820, CSF1P0, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, Amelogenin, D5S818, FGA