Frequency assessment of 25 SNPs in five different populations

Pietrangeli, Ilenia; Ottaviani, Enrica; Martone, Claudia; Gabriele, Luciano; Arcudi, Giovanni; Potenza, Saverio; Spinella, Aldo; Giardina, Emiliano; Novelli, Giuseppe

doi:10.1016/j.fsigen.2010.01.017

« Previous Next »Forensic Science International: Genetics
Volume 4, Issue 5 , Pages e131-e133, October 2010

Frequency assessment of 25 SNPs in five different populations

Ilenia Pietrangeli
- Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, School of Medicine, University of Rome Tor Vergata, Rome, Italy
Enrica Ottaviani
- Department of Public Health-Institute of Forensic Medicine, Faculty of Medicine, University of Rome Tor Vergata, Rome, Italy
Claudia Martone
- Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, School of Medicine, University of Rome Tor Vergata, Rome, Italy
Luciano Gabriele
- Direzione Centrale Anticrimine, Servizio di Polizia Scientifica, Rome, Italy
Giovanni Arcudi
- Department of Public Health-Institute of Forensic Medicine, Faculty of Medicine, University of Rome Tor Vergata, Rome, Italy
Saverio Potenza
- Department of Public Health-Institute of Forensic Medicine, Faculty of Medicine, University of Rome Tor Vergata, Rome, Italy
Aldo Spinella
- Direzione Centrale Anticrimine, Servizio di Polizia Scientifica, Rome, Italy
Emiliano Giardina
- Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, School of Medicine, University of Rome Tor Vergata, Rome, Italy
- Corresponding author. Tel.: +39 06 72596072; fax: +39 06 20427313.
Giuseppe Novelli
- Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, School of Medicine, University of Rome Tor Vergata, Rome, Italy
- Division of Cardiovascular Medicine, Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States

Received 22 April 2009; received in revised form 26 January 2010; accepted 26 January 2010. published online 22 February 2010.

Abstract

Allele and genotype frequencies of 25 SNPs previously selected and validated for forensic purposes were assessed in 250 unrelated individuals originating from five different countries of Europe (Spain, Croatia, Bulgaria, Turkey and Serbia). All the SNPs generated extremely low F_st values confirming our previous results on Italian, African (Benin) and Asian (Mongolian) populations. As a consequence of such F_st values we observed similar values of random match probability across the populations: 2.26×10⁻¹⁰ in the Spanish population, 2.13×10⁻¹⁰ in the Croatian population, 4.21×10⁻¹⁰ in the Bulgarian population, 2.52×10⁻¹⁰ in the Serbian population and 1.46×10⁻¹⁰ in the Turkish population.