Frequency assessment of 25 SNPs in five different populations
Received 22 April 2009; received in revised form 26 January 2010; accepted 26 January 2010. published online 22 February 2010. Corrected Proof
Abstract
Allele and genotype frequencies of 25 SNPs previously selected and validated for forensic purposes were assessed in 250 unrelated individuals originating from five different countries of Europe (Spain, Croatia, Bulgaria, Turkey and Serbia). All the SNPs generated extremely low Fst values confirming our previous results on Italian, African (Benin) and Asian (Mongolian) populations. As a consequence of such Fst values we observed similar values of random match probability across the populations: 2.26×10−10 in the Spanish population, 2.13×10−10 in the Croatian population, 4.21×10−10 in the Bulgarian population, 2.52×10−10 in the Serbian population and 1.46×10−10 in the Turkish population.
aCentre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, School of Medicine, University of Rome Tor Vergata, Rome, Italy
bDepartment of Public Health-Institute of Forensic Medicine, Faculty of Medicine, University of Rome Tor Vergata, Rome, Italy
cDirezione Centrale Anticrimine, Servizio di Polizia Scientifica, Rome, Italy
dDivision of Cardiovascular Medicine, Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States