Population genetics of 17 Y-chromosomal STR loci in Yakutia

Thèves, Catherine; Balaresque, Patricia; Evdokimova, Larissa E.; Timofeev, Innokentevich V.; Alekseev, Anatoly N.; Sevin, André; Crubézy, Eric; Gibert, Morgane

doi:10.1016/j.fsigen.2010.01.018

« Previous Next »Forensic Science International: Genetics
Volume 4, Issue 5 , Pages e129-e130, October 2010

Population genetics of 17 Y-chromosomal STR loci in Yakutia

Catherine Thèves
- Laboratory AMIS, FRE N°2960, CNRS/UPS, 37 allées Jules Guesde, 31000 Toulouse, France
- Corresponding author. Tel.: +33 05 61 14 59 82; fax: +33 05 61 14 59 79.
Patricia Balaresque
- Department of Genetics, Adrian Building Lab G2,University of Leicester, University Road, Leicester LE17RH, United Kingdom
Larissa E. Evdokimova
- Hospital of the Viljujsk Ulus, Republic of Sakha, Russia
Innokentevich V. Timofeev
- Hospital of the Viljujsk Ulus, Republic of Sakha, Russia
Anatoly N. Alekseev
- Yakutsk State University, Republic of Sakha, Russia
André Sevin
- Laboratory AMIS, FRE N°2960, CNRS/UPS, 37 allées Jules Guesde, 31000 Toulouse, France
Eric Crubézy
- Laboratory AMIS, FRE N°2960, CNRS/UPS, 37 allées Jules Guesde, 31000 Toulouse, France
Morgane Gibert
- Laboratory AMIS, FRE N°2960, CNRS/UPS, 37 allées Jules Guesde, 31000 Toulouse, France

Received 29 April 2009; received in revised form 25 January 2010; accepted 26 January 2010. published online 24 February 2010.

Abstract

Haplotype and allele frequencies of 17 Y-chromosomal short tandem repeat (Y-STR) markers in a population sample of 133 Yakut male volunteers from two regions: Central (n=41) and Western Yakutia (n=92) were determined using the AmpFlSTR Yfiler PCR Amplification Kit (Applied Biosystems). A total of 65 haplotypes were identified in the Yakut population, with 15 haplotypes in Central sample and 54 haplotypes in Western sample. Haplotype diversity values of 0.79 and 0.96, and average gene diversity values of 0.14 and 0.41 were calculated for Central and Western samples, respectively. The Fst distances between both our Yakut populations with other Russian, Siberian and Chinese populations were represented by MDS plot. The graphical view demonstrated close distances between most Yakut populations and differences with other Siberian populations.