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Population genetics of 17 Y-chromosomal STR loci in Yakutia

Catherine ThèvesaCorresponding Author Informationemail addressemail address, Patricia Balaresqueb, Larissa E. Evdokimovac, Innokentevich V. Timofeevc, Anatoly N. Alekseevd, André Sevina, Eric Crubézya, Morgane Giberta

Received 29 April 2009; received in revised form 25 January 2010; accepted 26 January 2010. published online 24 February 2010.
Corrected Proof

Abstract 

Haplotype and allele frequencies of 17 Y-chromosomal short tandem repeat (Y-STR) markers in a population sample of 133 Yakut male volunteers from two regions: Central (n=41) and Western Yakutia (n=92) were determined using the AmpFlSTR Yfiler PCR Amplification Kit (Applied Biosystems). A total of 65 haplotypes were identified in the Yakut population, with 15 haplotypes in Central sample and 54 haplotypes in Western sample. Haplotype diversity values of 0.79 and 0.96, and average gene diversity values of 0.14 and 0.41 were calculated for Central and Western samples, respectively. The Fst distances between both our Yakut populations with other Russian, Siberian and Chinese populations were represented by MDS plot. The graphical view demonstrated close distances between most Yakut populations and differences with other Siberian populations.

a Laboratory AMIS, FRE N°2960, CNRS/UPS, 37 allées Jules Guesde, 31000 Toulouse, France

b Department of Genetics, Adrian Building Lab G2,University of Leicester, University Road, Leicester LE17RH, United Kingdom

c Hospital of the Viljujsk Ulus, Republic of Sakha, Russia

d Yakutsk State University, Republic of Sakha, Russia

Corresponding Author InformationCorresponding author. Tel.: +33 05 61 14 59 82; fax: +33 05 61 14 59 79.

PII: S1872-4973(10)00026-8

doi:10.1016/j.fsigen.2010.01.018