Allele frequencies of six non-CODIS miniSTR loci (D1S1627, D3S4529, D5S2500, D6S1017, D8S1115 and D9S2157) in three South African populations

Received 15 December 2009 published online 02 March 2010.
Corrected Proof

Abstract

The allele frequency of six non-CODIS miniSTR loci: D1S1627, D3S4529, D5S2500, D6S1017, D8S1115 and D9S2157 were investigated in three South African populations (Afrikaner, Asian Indian and Mixed Ancestry). Deviation from Hardy–Weinberg equilibrium was observed in the Mixed Ancestry population for the locus D9S2157. All loci showed a moderate degree of polymorphism with heterozygosity values >0.6 for all populations. The combined power of discrimination was: 0.999997723, 0.999997163 and 0.99999961 for Afrikaner, Asian Indian and Mixed Ancestry populations, respectively. The respective values for the combined power of exclusion in these populations were: 0.99, 0.99 and 0.98.

Keywords: Allele frequencies, MiniSTR, DNA typing, Population data, South Africa

Department of Biotechnology, University of the Western Cape, Private Bag X17, Bellville, Cape Town 7535, South Africa

Corresponding author. Tel.: +27 21 959 2080; fax: +27 21 959 3505.

PII: S1872-4973(10)00027-X

doi:10.1016/j.fsigen.2010.01.019

*Note: Add-ons open in a new browser window. Please disable any pop-up blocking software before viewing Add-ons.