Forensic Science International: Genetics
Volume 6, Issue 4 , Pages e106-e108, July 2012

Mitochondrial DNA control region variation in an autochthonous Basque population sample from the Basque Country

  • Sergio Cardoso
    • ,
  • María Jesús Villanueva-Millán

      Affiliations

    • Present address: Medicina Xenómica, Dpto. de Anatomía Patolóxica e Ciencias Forenses, Universidad de Santiago de Compostela, Santiago de Compostela, Spain.
    • ,
  • Laura Valverde
    • ,
  • Adrian Odriozola

      Affiliations

    • Present address: Dpto. Fisiología y Farmacología, Unidad de Medicina Legal, Facultad de Medicina, Universidad de Cantabria, Santander, Spain.
    • ,
  • Jose M. Aznar
    • ,
  • Sergio Piñeiro-Hermida

      Affiliations

    • Present address: Medicina Xenómica, Dpto. de Anatomía Patolóxica e Ciencias Forenses, Universidad de Santiago de Compostela, Santiago de Compostela, Spain.
    • ,
  • Marian M. de Pancorbo

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +34 945014528; fax: +34 945014458.

BIOMICs Research Group, Centro de Investigación y Estudios Avanzados “Lucio Lascaray”, Universidad del País Vasco UPV/EHU, Avda. Miguel de Unamuno 3, 01006 Vitoria-Gasteiz, Spain

Received 14 October 2011; received in revised form 7 December 2011; accepted 28 December 2011. published online 25 January 2012.

Abstract 

Mitochondrial control region (16024–576) sequences were generated from 106 samples from autochthonous Basques from the Autonomous Community of the Basque Country. It is especially important to generate mtDNA databases from isolated populations in order to maximize the power of discrimination of this molecular marker. It also represents a useful approach to carry out a more accurate haplogroup classification. This is the first database report of complete control region sequences in an autochthonous Basque population sample. Strict selection criteria of autochthonous individuals, automation of laboratory processing and independent reviews of the raw electropherograms ensure the high quality of these sequences and their utility as reference population data of the autochthonous Basque population.

Keywords: Mitochondrial DNA, Control region, Basque Country, Autochthonous Basques

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PII: S1872-4973(11)00237-7

doi:10.1016/j.fsigen.2011.12.007

Forensic Science International: Genetics
Volume 6, Issue 4 , Pages e106-e108, July 2012

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