Abstract
Allele and genotype frequencies for 13 autosomal STR loci included in the Promega
Powerplex 16 kit were assessed in 174 individuals from three Garifuna communities
of the Caribbean coasts of Honduras (Central America). For the 13 loci the observed
heterozygocity frequencies ranged from 0.571 for the D5S818 locus to 0.939 for the
D18S51 locus, both in the Corozal population. Deviations from Hardy–Weinberg equilibrium,
as well as pairs of loci in linkage disequilibrium (even after Bonferroni corrections
of the level of statistical significance) and high Fis values were observed. These “spurious” results are probably caused by population
substructure (Wahlund effect within communities) and high endogamy.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Forensic Science International: GeneticsAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Pueblos Indígenas y Garífuna de Honduras: Una Caracterización.Editorial Guaymuras, Tegucigalpa2000 (pp. 257–261)
- The anthropological genetics of the Black Caribs (Garifuna) of Central America and the Caribbean.Year Book Phys. Anthropol. 1983; 25: 155-186
- Factors underlying decreasing fertility among the Garifuna of Honduras.Am. J. Phys. Anthropol. 1983; 60: 177
- The Garífuna: weaving a future from a tangled past.Natl. Geogr. Soc. Mag. 2001; : 102-107
- The Black Caribs (Garifuna) of Livingston, Guatemala: genetic markers and admixture estimates.Hum. Biol. 1981; 53: 87-103
- Blood group, serum protein, and red cell enzyme polymorphisms, and admixture among the Black Caribs and Creoles of Central America and the Caribbean.in: Crawford M.H. Current Developments in Anthropological Genetics, vol. III: Black Caribs: A Case Study of Biocultural Adaptation. Plenum Press, New York1982
- Anthropogenetics in a hybrid population. The Black Caribs studies.in: Crawford M.H. Current Developments in Anthropological Genetics, vol. III: Black Caribs: A Case Study of Biocultural Adaptation. Plenum Press, New York1984
- Origin and maintenance of genetic variation on Black Carib populations of St. Vincent and Central America.in: Roberts D.F. De Stefano G. Genetic Variation and Its Maintenance in Tropical Populations. Cambridge University Press, Cambridge, UK1986
- Mitochondrial DNA polymorphisms in Carib people of Belize.Proc. Roy. Soc. Lond. B. 1997; 264: 1217-1224
- Population structure of native Americans.The Origins of Native Americans. Evidence from Anthropological Genetics. Cambridge University Press, Cambridge, UK1998
- Estimation of average heterozygosity and genetic distance from a small number of individuals.Genetics. 1978; 89: 583-590
- Blood samples: probability of discrimination.J. Forensic Sci. Soc. 1972; 12: 355
- Evaluation of 13 tandem repeat loci for use in personal identification applications.Am. J. Hum. Genet. 1994; 55: 175-189
- Paternity index calculations in single locus hypervariable DNA probes: validation and other studies.in: Proceedings for the International Symposium on Human Identification, Promega Corporation, Madison, WI1989: 21-53
- Mendelian proportions in a mixed population.Science. 1908; 28: 49-50
- Über den Nachweis der Varerburg beim Menschen.Jahresheft er Vaterländische Naturkunde in Württemberg. 1908; 64: 368-382
- Performing the exact test of Hardy–Weinberg proportions for multiple alleles.Biometrics. 1992; 48: 361-372
- Genetic Data Analysis II.Sinahuer Associates, Publishers, Sunderland, MA1996
- Genetic Data Analysis: Computer Program for Analysis of the Allelic Data.Department of Statistics, North Carolina State University, Raleigh, NC2000
- Estimating F-statistics for the analysis of population structure.Evolution. 1984; 38: 1358-1370
- Arlequin (ver. 1.1): A Software Environment for the Analysis of Genetic Population Data, Genetics and Biometry Laboratory.University of Geneva, Switzerland1997
- Zygotic associations and multilocus statistics in a nonequilibrium diploid population.Genetics. 2000; 155: 1449-1458
- Analysis of the CODIS autosomal STR loci in four main Colombian regions.Forensic Sci. Int. 2003; 137: 67-73
- Genotype profiles for six population groups at the 13 CODIS short tandem repeat core loci and other PCR based loci.Forensic Sci. Commun. Fed. Bur. Investig. 1999; 1 (Available online at: http://www.fbi.gov/hq/lab/fsc/backissu/july1999/budowle.htm)
- Genetic profile of a multi-ethnic population from Guiné-Bissau (West African coast) using the new PowerPlex® 16 System Kit.Forensic Sci. Int. 2002; 129: 78-80
- Population data on nine short tandem repeat loci and D1S80 in a sample from Honduras.Forensic Sci. Int. 2004; 141: 39-40
- Population genetic data for 18 STR loci in Costa Rica.Forensic Sci. Int. 2007; 168: 85-88
- Genetic structure of forensic populations.Proc. Natl. Acad. Sci. 1992; 89: 2556-2560
- The Evaluation of Forensic DNA Evidence.National Academy Press, Washington, DC1996 (pp. 89–124)
- Publication of population data of human polymorphisms.Forensic Sci. Int. 2000; 110: 3-5
Article info
Publication history
Published online: March 31, 2008
Accepted:
February 17,
2008
Received in revised form:
January 5,
2008
Received:
August 8,
2007
Identification
Copyright
© 2008 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.