One hundred thirty male individuals, strictly selected for their geographical origin and for typical regional surnames were submitted to the analysis. 17 STRs (short tandem repeats) loci and 19 SNPs binary markers (single nucleotide polymorphisms) of male-specific region of the Y chromosome (MSY) were typed to well characterize the selected population of Modena province. The availability of joint distribution of MSY haplotypes and haplogroup frequencies is becoming an important tool for both human evolutionary studies and forensic investigation, but large databases of complete Y-lineages are needed for a better understanding of the power of the combined use of Y-specific polymorphisms.
A total of 129 haplotypes and 9 haplogroups were found and R1b haplogroup with a frequency of 67.7% was the most frequent, as expected because of the geographical location of the sample (Northwestern Italy). The Modena Y-lineages (STRs and SNPs independently) were also compared with published data of other neighbouring populations’ samples.
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- Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material.Biotechniques. 1991; 10: 506-513
- Development of multiplex PCRs for evolutionary and forensic applications of 37 human Y chromosome SNPs.Forensic Sci. Int. 2006; 157: 23-35
- Hierarchical analysis of 30 Y-chromosome SNPs in European populations.Int. J. Legal Med. 2005; 119: 10-15
- Molecular Evolutionary Genetics.Columbia University Press, New York1987
- Arlequin ver. 3.0: an integrated software package for population genetics data analysis.Evol. Bioinform. Online. 2005; 1: 47-50
- Signature of recent historical events in the European Y-chromosomal STR haplotype distribution.Hum. Genet. 2005; 116: 279-291
- Messages through bottlenecks: on the combined use of slow and fast evolving polymorphic markers on the human Y chromosome.Am. J. Hum. Genet. 2000; 67: 1055-1061
- Male haplotypes and haplogroups differences between urban (Rimini) and rural area (Valmarecchia) in Romagna region (North Italy).Forensic Sci. Int. 2007; https://doi.org/10.1016/j.forsciint.2007.06.007
- Y-chromosome genetic structure in sub-Apennine populations of Central Italy by SNP and STR analysis.Int. J. Legal Med. 2007; 121: 234-237
- Y chromosome genetic variation in the Italian peninsula is clinal and supports an admixture model for the Mesolithic-Neolithic encounter.Mol. Phylogenet. Evol. 2007; 44: 228-239
- Clinal patterns of human Y chromosomal diversity in continental Italy and Greece are dominated by drift and founder effects.Mol. Phylogenet. Evol. 2003; 28: 387-395
- The genetic legacy of Paleolithic Homo sapiens in extant Europeans: a Y chromosome perspective.Science. 2000; 290: 1155-1159
- Population data for 12 Y-chromosome STRs in a sample from Brescia (northern Italy).Forensic Sci. Int. 2005; 152: 83-87
- Y-chromosomal STR haplotypes in a Northeast Italian population sample using 17plex loci PCR assay.Int. J. Legal Med. 2006; 120: 56-59
- Forensic Sci. Int.: Genet. 2007; 1: 83-87
- Grouping of Y-STR haplotypes discloses European geographic clines.Forensic Sci. Int. 2003; 134: 172-179
- Publication of population data of human polymorphisms.Forensic Sci. Int. 2000; 110: 3-5
Published online: June 24, 2008
Accepted: May 7, 2008
Received in revised form: March 21, 2008
Received: November 9, 2007
© 2008 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.