A sample of 265 unrelated individuals inhabiting five governorates in Upper (south) Egypt was collected with informed consent. The samples were amplified using the AmpFℓSTR®Identifiler™PCR Amplification Kit (containing 15 loci: D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA), and genotyped subsequent to capillary electrophoresis. Statistical analysis of the generated data indicated neither departure from expectation of Hardy–Weinberg Equilibrium (HWE) in most of the tested loci nor dependence of alleles between loci. All tested loci were polymorphic; the most discriminating is D18S51 while the least is TPOX. The combined power of exclusion was 0.99999868 and the combined match probability was 1.93 × 10−18. The genetic diversity of the Upper Egyptians was compared with those of other populations at the local, regional and global levels.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Forensic Science International: Genetics
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- Extraction of single-copy nuclear DNA from forensic specimens with a variety of postmortem histories.J. Forensic Sci. 1997; 42: 1032-1038
- Tools for analysis of population statistics.Prof DNA. 1999; 2: 14-16
- Arlequin (version 3.0): an integrated software package for population genetics data analysis.Evol. Bioinform. Online. 2005; 1: 47-50
- GENALEX 6: genetic analysis in Excel. Population genetic software for teaching and research.Mol. Ecol. Notes. 2006; 6: 288-295
P. de Knijff (2006) personal communication.
- A human genome diversity cell line panel.Science. 2002; 296: 261-262
E. Abd AlSalam, A report presented to the Regional Consultation on Community Genetic Services, Hereditary disorders, World Health Organization Regional Office for the Eastern Mediterranean, Alexandria, 1994.
- Population genetic studies on the tetrameric short tandem repeat loci D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820 in Egypt.Forensic Sci. Int. 1999; 104: 23-31
- Allele frequency distribution of Power Plex 1.2 and Profiler Plus short tandem repeats (STR) loci in Egyptian population.J. Forensic Sci. 2003; 48: 889-890
- STR population data for 10 STR loci including the GenePrint PowerPlex 1.2 kit from El-Minia (Central Egypt).Forensic Sci. Int. 2001; 117: 233-234
- Allele frequencies of 15 short tandem repeats (STRs) in three Egyptian populations of different ethnic groups.Forensic Sci. Int. 2007; 169: 260-265
- Allelic distribution of nine short tandem repeat (STR), HLA-DQA1, and polymarker loci in an Omani sample population.Forensic Sci. Int. 2000; 109: 81-85
- Qatari DNA variation at a crossroad of human migrations.Hum. Hered. 2006; 61: 67-79
- Significant differences between Yemenite and Egyptian STR profiles and the influence on frequency estimations in Arabs.Int. J. Legal Med. 2001; 114: 211-214
- Allele frequencies of nine STR loci of Jewish and Arab populations in Israel.Int. J. Legal Med. 2002; 116: 184-186
- Turkish population data for 15 STR loci by multiplex PCR.J. Forensic Sci. 2005; 50: 737-738
- Data on nine STR loci used for forensic and paternity testing in the Greek Cypriot population of Cyprus.Forensic Sci. Int. 2001; 123: 225-226
- Northwest Italian population data for thirteen tetrameric and two pentameric STR loci.J. Forensic Sci. 2004; 49: 405-406
- Brief communication: Y-chromosome haplotypes in Egypt.Am. J. Phys. Anthropol. 2003; 121: 63-66
- The making of the African mtDNA landscape.Am. J. Hum. Genet. 2002; 71: 1082-1111
- Publication of population data of human polymorphisms.Forensic Sci. Int. 2000; 110: 3-5
Published online: July 03, 2008
Accepted: May 12, 2008
Received: March 1, 2008
© 2008 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.