Abstract
The Karimojong, an African group from the Karamoja region of Northeast Uganda, were
genetically analysed using a decaplex system for X chromosome short tandem repeats
(X-STRs). A total of 255 individuals (117 males and 138 females) were genotyped for
the following loci: DXS8378, DXS9898, DXS7133, GATA31E08, GATA172D05, DXS7423, DXS6809,
DXS7132, DXS9902 and DXS6789. Allele frequencies and parameters for forensic evaluation
were calculated for each STR. No association was found between any pairs of loci studied.
DXS6789 was the most polymorphic marker in this sample, followed by DXS6809, with
gene diversities of 84.79% and 83.94%, respectively. The less discriminating locus
observed was DXS7133, with a gene diversity of 39.79%. High overall values of power
of discrimination were obtained for female (1 in 1.8 × 1010) and male samples (1 in 1.6 × 106), as well as high power of exclusion in father/mother/daughter trios (99.9997%),
in father daughter duos (99.9862%) and in half sisters with same father (99.0331%).
These results confirm the potential of this 10-plex in parentage testing and in human
identification.
Keywords
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References
- Population data defined by 15 autosomal STR loci in Karamoja population (Uganda) using AmpF/STR Identifiler kit.Forensic Sci. Int.: Gen. 2009; 3: e55-e58
- Results of the GEP-ISFG collaborative study on a X-STR Decaplex.Forensic Sci. Int.: Gen. 2008; 1: 677-679
L. Gusmão, P. Sánchez-Diz, C. Alves, I. Gomes, M.T. Zarrabeitia, M. Abovich, I. Atmetlla, C. Bobillo, L. Bravo, J. Builes, L. Cainé, R. Calvo, E. Carvalho, M. Carvalho, R. Cicarelli, D. Corach, M. Espinoza, O. García, M. Malaghini, J. Martins, F. Pinheiro, M.J. Porto, E. Raimondi, J.A. Riancho Jr.III, A. Rodríguez, A. Rodríguez, B. Rodríguez, S. Silva, C. Tavares, U. Toscanini, C.Vullo, M. Whittle, I.Yurrebaso, A. Carracedo, A. Amorim, A GEP-ISFG collaborative study on the optimization of an X-STR Decaplex: data on 15 Iberian and Latin American populations. Int. J. Legal Med., doi:10.1007/s00414-008-0309-4.
- Arlequin ver 30: an integrated software package for population genetics data analysis.Evol. Bioinform. Online. 2005; 1: 47-50
- Development of a highly polymorphic STR marker for identity testing purposes at the human androgen receptor gene (HUMARA).J. Forensic Sci. 1998; 43: 1046-1049
- Analysis of 10 X-STRs in three African populations.Forensic Sci. Int. Genet. 2007; 1: 208-211
- Genetic analysis of three US population groups using an X-chromosomal STR decaplex.Int. J. Legal Med. 2007; 121: 198-203
- Allele frequencies of 11 X-chromosomal loci in a population sample from Ghana.Int. J. Legal Med. 2008; https://doi.org/10.1007/s00414-008-0251-5
- Publication of population data of human polymorphisms.Forensic Sci. Int. 2000; 110 (3–5)
Article info
Publication history
Published online: December 22, 2008
Accepted:
October 26,
2008
Received in revised form:
October 15,
2008
Received:
October 6,
2008
Identification
Copyright
© 2008 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
