A set of autosomal single nucleotide polymorphism (SNP) loci was analyzed using the 52-plex assay previously described by Sanchez et al. [J.J. Sanchez, C. Phillips, C. Borsting, K. Balogh, M. Bogus, M. Fondevila, C.D. Harrison, E. Musgrave-Brown, A. Salas, D. Syndercombe-Court, P.M. Schneider, A. Carracedo, N. Morling, A multiplex assay with 52 single nucleotide polymorphisms for human identification, Electrophoresis 27 (2006) 1713–1724] in 140 samples of unrelated individuals born in the Colombian regions of, Risaralda, Caldas, Quindio, Antioquia, Tolima and Valle, and 164 samples of unrelated individuals with declared Native American ancestry from Colombia. Allele frequencies and statistical parameters of forensic interest are presented for the 52 SNPs. All loci were in agreement with Hardy–Weinberg equilibrium while comparisons with population samples of Argentina, Portugal, Spain, Mozambique, and Taiwan revealed significant differences in allele frequency distributions.
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- A multiplex assay with 52 single nucleotide polymorphisms for human identification.Electrophoresis. 2006; 27: 1713-1724
- Performing the exact test of Hardy Weinberg proportion for multiple alleles.Biometrics. 1992; 48: 361-372
- Arlequin ver 2000: A Software for Population Genetics Data Analysis.Genetics and Biometry Laboratory, University of Geneva, Switzerland2005 (URL: http://lgb.unige.ch/arlequin/)
- Tools for Analysis of Population Statistics Profiles in DNA.Promega Corp., 1999
- Resolving relationship tests that show ambiguous STR results using autosomal SNPs as supplementary markers.Forensic Sci. Int. Genet. 2008; 2: 198-204
- Identification of skeletal remains using short-amplicon marker analysis of severely degraded DNA extracted from a decomposed and charred femur.Forensic Sci. Int. Genet. 2008; 2: 212-218
- An assessment of the utility of single nucleotide polymorphisms (SNPs) for forensic purposes.Int. J. Legal. Med. 2001; 114: 204-210
- SNPs in forensic genetics: a review on SNP typing methodologies.Forensic Sci. Int. 2005; 154: 181-194
- Analysis of artificially degraded DNA using STRs and SNPs—results of a collaborative European (EDNAP) exercise.Forensic Sci. Int. 2006; 164: 33-44
Published online: January 27, 2009
Accepted: December 8, 2008
Received: November 3, 2008
© 2008 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.