Abstract
Allele frequency distribution of 15 short tandem repeat (STR) loci (D8S1179, D21S11,
D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51,
D5S818, and FGA) was studied in a sample of 120 unrelated native Qatari population
using the AmpFISTR® Identifiler kit (Applied Biosystems, Foster city, CA, USA). All loci met Hardy–Weinberg
expectations and there was no evidence for linkage disequilibrium between any of the
marker pairs. The most discriminating locus was D2S1338 with a power of discrimination
(PD) of 0.969, while the lowest one was TPOX, yet with a PD of 0.821. For all the
15 loci, the combined PD and the combined power of exclusion (PE) were respectively
0.99999999 and 0.99999744. Thus the probability of finding two individuals bearing
an identical 15 locus DNA profile is one in 108 native Qatari subjects and this surpasses largely the present day Qatari natives
consisting of around 3.5 × 105 individuals. The results of this study demonstrate the usefulness and reliability
of the AmpFISTR® Identifiler kit for individual identification in forensic studies in the native Qatari
population, despite the current practice of high inbreeding.
Keywords
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References
AmpFISTR® Identifiler™ PCR Amplification Kit User's Manual. Applied Biosystems, Foster city, CA, USA, (2001).
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Article info
Publication history
Published online: February 02, 2009
Accepted:
December 20,
2008
Received in revised form:
December 11,
2008
Received:
March 10,
2008
Identification
Copyright
© 2009 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
