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Announcement of Population Data| Volume 4, ISSUE 1, e25-e26, December 2009

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Genetic data on 15 STR autosomal loci for a sample population of the Northern Region of the State of Rio de Janeiro, Brazil

  • Eduardo Leal Rodrigues
    Affiliations
    Núcleo de Diagnóstico e Investigação Molecular (NUDIM), Laboratório de Biotecnologia, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Avenida Alberto Lamego 2000, Parque Califórnia, Campos dos Goytacazes CEP 29013-602, RJ, Brazil
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  • Filipe Brum Machado
    Affiliations
    Núcleo de Diagnóstico e Investigação Molecular (NUDIM), Laboratório de Biotecnologia, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Avenida Alberto Lamego 2000, Parque Califórnia, Campos dos Goytacazes CEP 29013-602, RJ, Brazil

    Hospital Escola Álvaro Alvim, Rua Barão da Lagoa Dourada 409, Pelinca, Campos dos Goytacazes CEP 28.035-010, RJ, Brazil
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  • Marilia Mothé Arruda
    Affiliations
    Hospital Escola Álvaro Alvim, Rua Barão da Lagoa Dourada 409, Pelinca, Campos dos Goytacazes CEP 28.035-010, RJ, Brazil
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  • Rodrigo Soares de Moura-Neto
    Affiliations
    Instituto de Biologia, Departamento de Genética, Universidade Federal do Rio de Janeiro, Rio de Janeiro CEP 21941-910, RJ, Brazil
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  • Enrique Medina-Acosta
    Correspondence
    Corresponding author. Tel.: +55 22 2726 6758; fax: +55 22 2726 6758.
    Affiliations
    Núcleo de Diagnóstico e Investigação Molecular (NUDIM), Laboratório de Biotecnologia, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Avenida Alberto Lamego 2000, Parque Califórnia, Campos dos Goytacazes CEP 29013-602, RJ, Brazil
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Published:February 24, 2009DOI:https://doi.org/10.1016/j.fsigen.2009.01.008

      Abstract

      Allele frequencies data, paternity and forensic parameters for 15 autosomal short tandem repeat (STR) autosomal markers (D8S1179, D21S11, D7S820, CSF1PO, D5S818, D3S1358, TH01, D13S317, D16S539, D2S1338, TPOX, D19S433, vWA, D18S51, FGA) were determined for a sample of 494 unrelated individuals undergoing kinship analysis and molecular cytogenetic testing from the population of the city of Campos dos Goytacazes, Northern State of Rio de Janeiro, Brazil. The loci with the highest polymorphism information content were D18S51 (0.874), D2S1338 (0.853), FGA (0.852), D21S11 (0.838). The combined power of discrimination and the combined power of exclusion were 0.999999999999999 and 0.999526684, respectively. At the available common loci CSF1PO, TH01, TPOX, vWA, D16S539, D7S820 and D13S317, allele frequencies were compared with population databases from State of Alagoas, State of Amazonas, State of São Paulo (Brazilian mulattoes, descendants of Europeans, Africans or Asians), State of Mato Grosso do Sul and State of Rio de Janeiro. No significant distances were observed. The interpopulation genetic distance (Fst coefficients) to the present database, ranged 0.0022 (p = 0.446) (Northern State Rio de Janeiro-State of São Paulo European-descendants) to 0.0138 (p = 0.993) (Northern State Rio de Janeiro-State of São Paulo Asian-descendants). The Asian-descendants Brazilians are the least admixed. All other groups are admixed as one unique population.

      Keywords

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      References

      1. A. Tereba, Tools for analysis of population statistics (free program distributed by Promega Corporation USA over the internet from http://www.promega.com/geneticidtools/powerstats/Default.htm), Profiles in DNA 2 (1999) 14–16.

        • Brenner C.H.
        Symbolic kinship program.
        Genetics. 1997; 145: 535-542
      2. T. Ota, DISPAN: Genetic Distance and Phylogenetic Analysis. [Online] 1993 November 19 2003 [cited 2008 August 5]; Available from: http://www.bio.psu.edu/people/faculty/Nei/Lab/dispan2.htm.

      3. L. Excoffier, G. Laval, S. Schneider, Arlequin (version 3.0): an integrated software package for population genetics data analysis, Evol. Bioinform. Online 1 (2005) 47–50.

      4. P.O. Lewis, D. Zaykin, Genetic data analysis: computer program for the analysis of allelic data. [Online] 2001 January 11 2008 [cited 2008 August 5]; [Available from: http://www.eeb.uconn.edu/people/plewis/software.php.

      5. R.D. Page, TreeView: an application to display phylogenetic trees on personal computers (free program distributed by the author over the internet from http://taxonomy.zoology.gla.ac.uk/rod/treeview.html), Comput. Appl. Biosci. 12 (1996) 357–358.

        • Ferreira da Silva L.A.
        • Pimentel B.J.
        • Almeida de Azevedo D.
        • Pereira da Silva E.N.
        • Silva dos Santos S.
        Allele frequencies of nine STR loci – D16S539, D7S820, D13S317, CSF1PO, TPOX, TH01, F13A01, FESFPS and vWA – in the population from Alagoas, Northeastern Brazil.
        Forensic Sci. Int. 2002; 130: 187-188
        • Rodrigues E.M.
        • Palha Tde J.
        • dos Santos S.E.
        Allele frequencies data and statistic parameters for 13 STR loci in a population of the Brazilian Amazon Region.
        Forensic Sci. Int. 2007; 168: 244-247
        • Bydlowski S.P.
        • de Moura-Neto R.S.
        • Soares R.P.
        • Silva R.
        • Debes-Bravo A.A.
        • Morganti L.
        Genetic data on 12 STRs (F13A01, F13B, FESFPS, LPL, CSF1PO, TPOX, TH01, vWA, D16S539, D7S820, D13S317, D5S818) from four ethnic groups of Sao Paulo, Brazil.
        Forensic Sci. Int. 2003; 135: 67-71
        • Silva D.A.
        • Crouse C.A.
        • Chakraborty R.
        • Goes A.C.
        • Carvalho E.F.
        Statistical analyses of 14 short tandem repeat loci in Brazilian populations from Rio de Janeiro and Mato Grosso do Sul states for forensic and identity testing purposes.
        Forensic Sci. Int. 2004; 139: 173-176
        • Goés A.C.
        • da Silva D.A.
        • Fonseca Gil E.H.
        • da Silva M.T.
        • Pereira R.W.
        • de Carvalho E.F.
        Allele frequencies data and statistic parameters for 16 STR loci-D19S433, D2S1338, CSF1PO, D16S539, D7S820, D21S11, D18S51, D13S317, D5S818, FGA, Penta E, TH01, vWA, D8S1179, TPOX, D3S1358-in the Rio de Janeiro population, Brazil.
        Forensic Sci. Int. 2004; 140: 131-132
        • Silva R.
        • Moura-Neto R.S.
        Genetic diversity and admixture data on 11 STRs (F13B, TPOX, CSF1PO, F13A01, D7S820, LPL, TH01, vWA, D13S317, FESFPS, and D16S539) in a sample of Rio de Janeiro European-descendants population, Brazil.
        Forensic Sci. Int. 2004; 142: 51-53
        • Lincoln P.
        • Carracedo A.
        Publication of population data of human polymorphisms.
        Forensic Sci. Int. 2000; 110: 3-5