Allelic frequencies of 48 informative insert-delete (INDEL) loci were obtained from a sample set of 130 unrelated individuals living in Macapá, a city located in the northern Amazon region, in Brazil. The values of heterozygosity (H), polymorphic information content (PIC), power of discrimination (PD), power of exclusion (PE), matching probability (MP) and typical paternity index (TPI) were calculated and showed the forensic efficiency of these genetic markers. Based on the allele frequency obtained for the population of Macapá, we estimated an interethnic admixture for the three parental groups (European, Native American and African) of, respectively, 50%, 21% and 29%. Comparing these allele frequencies with those of other Brazilian populations and the parental populations, statistically significant distances were found. The interpopulation genetic distance (FST coefficients) to the present database ranged from FST = 0.0431 (p < 0.00001) between Macapá and Belém to FST = 0.266 (p < 0.00001) between Macapá and the Native American group.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Forensic Science International: Genetics
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- História dos Índios no Brasil.Companhia das Letras, FAPESP, SMC-PMSP, São Paulo1995
- The Atlantic Slave Trade: A Census.University of Wisconsin Press, Madison, WI1969
- The Evolution and Genetics of Latin American Population.Cambridge University Press, Cambridge, UK2002
- The indigenous contribution to the formation of the population of the Brazilian Amazon Region.Genet. Mol. Biol. 1995; 18: 311-315
- Contribution for an African autosomic STR database (AmpF/STR Identifier and Powerplex 16 System) and a report on genotypic variations.Forensic Sci. Int. 2004; 139: 201-205
- MtDNA haplogroup analysis of black Brazilian and sub-Saharan populations: implications for the Atlantic slave trade.Hum. Biol. 2006; 78: 29-41
- Population data for Y-chromosome haplotypes defined by 17 STRs (AmpFlSTR YFiler) in Portugal.Forensic Sci. Int. 2007; 171: 250-255
- Differential contribution of indigenous men and women to the formation of an urban population in the Amazon region as revealed by mtDNA and Y-DNA.Am. J. Phys. Anthropol. 1999; 109: 175-180
- The indigenous contribution to the formation of the population of the Brazilian Amazon Region.Rev. Bras. Genet. 1995; 18: 311-315
- Assessing individual interethnic admixture and population substructure using a 48-insertion-deletion (INSEL) ancestry-informative marker (AIM) panel.Hum. Mutat. 2010; 31: 184-190
- Interethnic variability and admixture in Latin America – social implications.Rev. Biol. Trop. 2004; 52: 405-415
- Admixture studies in Latin America: from the 20th to the 21st century.Hum. Biol. 2000; 72: 155-177
- Isolation of DNA from mammalian cells.in: Ford N. Nolan C. Ferguson M. Molecular Cloning. Cold Spring Harbor Laboratory Press, New York1989: 916-919
- Arlequin: A Software for Population Genetics Data Analysis, Ver. 2.000.Genetics and Biometry Lab, Department of Antropology, University of Geneva, 2000
A. Tereba, Tools for Analysis of Population Statistics, Profiles in DNA, vol. 2, no. 3, Home page at http://www.promega.com/geneticidtools
P.O. Lewis, D. Zaykin, Genetic Data Analysis: Computer Program for the Analysis of Allelic Data. Available from: http://www.eeb.uconn.edu/people/plewis/software.php
- DNA recommendations – report concerning further recommendations of the DNA Commission of the ISFH regarding PCR-based polymorphisms in STR (short tandem repeat) systems.Forensic Sci. Int. 1994; 69: 103-104
Published online: May 03, 2011
Accepted: April 2, 2011
Received in revised form: February 22, 2011
Received: October 8, 2010
© 2011 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.