Abstract
Seventeen Y-chromosomal short tandem repeats (STRs) were analyzed in 347 healthy,
unrelated, autochthonous males from the Andalusian provinces of Huelva (N = 167) and Granada (N = 180). AmpFlSTR Y-filer PCR Amplification kit (Applied Biosystems) was used to type
the Y-STR markers. A total of 156 and 166 different haplotypes for the 17 Y-STR set
were detected in Huelva, and Granada, respectively. The same haplotype diversity was
found for both samples (0.998 ± 0.001), and the overall discrimination capacity was 0.904. The most common minimal
haplotype (DYS19, DYS389 I, DYS389 II, DYS390, DYS391, DYS392, DYS393) in both subpopulations
was 14-13-16-24-11-13-13, which is also the most frequent haplotype among Atlantic
European populations. Comparison analysis using pairwise RST values and Analysis of Molecular Variance (AMOVA) revealed a significant genetic
distance between our Andalusian samples and other ones from the northern Iberian fringe
(including Basque and Pyrenean populations). However, results from the multi-dimensional
scaling analysis (MDS) yielded a well-defined group of Iberian populations separated
from the other Mediterranean clusters observed.
Keywords
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Article info
Publication history
Published online: June 13, 2011
Accepted:
May 11,
2011
Received in revised form:
May 10,
2011
Received:
March 3,
2011
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Copyright
© 2011 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.