Abstract
Allele frequency distributions for 15 STR loci (AmpFlSTR Identifiler kit) were estimated in 825 volunteers of the following eight Mexican-Amerindian
populations from two geographical regions: (1) North: Tarahumara (204), Mayo (45), Seri (28), and Guarijío (17); (2) Northwest: Tepehuano (123), Mexicanero (84), Cora (85), and Huichol (239). Genotype frequency
distribution was in agreement with Hardy–Weinberg expectations for all 15 STRs, excepting
for two loci (D13S317 and FGA) in the Huichol population. The power of discrimination
and power of exclusion values were both larger than 0.99999. These STR databases will
support the correct interpreting of DNA profiles in paternity testing and forensic
cases in Mexican-Amerindian groups from these regions, until know poorly studied.
Genetic distances and pairwise comparisons were estimated between populations. A significant
genetic differentiation was observed between these Mexican-Amerindian groups (FST = 3.43%; p = 0.0000) that was 10 times larger than the observed between Mestizos (FST = 0.34%), which represent most of the Mexican population (∼90%). This result was in
agreement with the incapability to cluster these Native American populations by geographic
criteria. Pre-Colombian descriptions of Aridoamerica, including the North region of
Mexico, suggest genetic drift effects to explain this noticeable population differentiation
of Mexican-Amerindian groups.
Keywords
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Article info
Publication history
Published online: March 07, 2013
Accepted:
February 11,
2013
Received in revised form:
January 31,
2013
Received:
August 20,
2012
Identification
Copyright
© 2013 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
