Allele frequency distributions for 15 STR loci (AmpFlSTR Identifiler kit) were estimated in 825 volunteers of the following eight Mexican-Amerindian populations from two geographical regions: (1) North: Tarahumara (204), Mayo (45), Seri (28), and Guarijío (17); (2) Northwest: Tepehuano (123), Mexicanero (84), Cora (85), and Huichol (239). Genotype frequency distribution was in agreement with Hardy–Weinberg expectations for all 15 STRs, excepting for two loci (D13S317 and FGA) in the Huichol population. The power of discrimination and power of exclusion values were both larger than 0.99999. These STR databases will support the correct interpreting of DNA profiles in paternity testing and forensic cases in Mexican-Amerindian groups from these regions, until know poorly studied. Genetic distances and pairwise comparisons were estimated between populations. A significant genetic differentiation was observed between these Mexican-Amerindian groups (FST = 3.43%; p = 0.0000) that was 10 times larger than the observed between Mestizos (FST = 0.34%), which represent most of the Mexican population (∼90%). This result was in agreement with the incapability to cluster these Native American populations by geographic criteria. Pre-Colombian descriptions of Aridoamerica, including the North region of Mexico, suggest genetic drift effects to explain this noticeable population differentiation of Mexican-Amerindian groups.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Forensic Science International: Genetics
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- Pre-hispanic mesoamerican demography approximates the present-day ancestry of Mestizos throughout the territory of Mexico.Am. J. Phys. Anthropol. 2009; 139: 284-294
- Genetic diversity of 15 STRs in Choles from Northeast of Chiapas (Mexico).J. Forensic Sci. 2005; 50: 1499-1501
- Delineating genetic relationships among the Maya.Am. J. Phys. Anthropol. 2008; 135: 329-347
- Analyzing the genetic structure of the Tepehua in relation to other neighboring Mesoamerican populations: a study based on allele frequencies of STRs markers.Am. J. Hum. Biol. 2008; 20: 605-613
- Origin and genetic differentiation of three Native Mexican groups (Purépechas, Triquis and Mayas): contribution of CODIS-STRs to the history of human populations of Mesoamerica.Ann. Hum. Biol. 2010; 37: 801-819
- Genetic characterization of indigenous peoples from Oaxaca, Mexico, and its relation to linguistic and geographic isolation.Hum. Biol. 2010; 82: 409-432
- Southwest Archaeology in the Twentieth Century.University of Utah Press, Salt Lake City2005
Instituto Nacional Indigenista, Etnografía contemporánea de los pueblos indígenas de México, Región Noroeste, INI (Ed.), México, DF, 1995.
- An Update: The Evaluation of Forensic DNA Evidence.National Academy Press, Washington, DC1996
- Microsatellite variation and the differentiation of modern humans.Hum. Genet. 1997; 99: 1-7
A. Tereba, Tools for analysis of population statistics. Profiles in DNA: Promega Corp., 2001.
P.O. Lewis, D. Zaykin, (GDA), Genetic Data Analysis: Computer Program for the Analysis of Allelic Data Version 1.0 2001.
- Arlequin ver. 3. 0: an integrated software package for population genetic analysis.Evol. Bioinform. Online. 2005; 1: 47-50
- A simulated annealing approach to define the genetic structure of populations.Mol. Ecol. 2002; 11: 2571-2581
- Cultura de maíz-peyote-venado, sustentabilidad del pueblo Wixarika.Universidad de Guadalajara, Jalisco, México2007
- The Garífuna (Black Carib) people of the Atlantic coasts of Honduras: population dynamics, structure, and phylogenetic relations inferred from genetic data, migration matrices, and isonymy.Am. J. Hum. Biol. 2010; 22: 36-44
- A novel measure of genetic distance for highly polymorphic tandem repeat loci.Mol. Biol. Evol. 1995; 12: 914-920
- Genetic variation among four Mexican Populations (Huichol, Purépecha, Tarahumara, and Mestizo) revealed by two VNTRs and four STRs.Hum. Biol. 2000; 72: 983-995
Published online: March 07, 2013
Accepted: February 11, 2013
Received in revised form: January 31, 2013
Received: August 20, 2012
© 2013 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.