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Published online: January 23, 2014
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- Evaluation of next generation mtGenome sequencing using the Ion Torrent Personal Genome Machine (PGM)Forensic Science International: GeneticsVol. 7Issue 5
- PreviewInsights into the human mitochondrial phylogeny have been primarily achieved by sequencing full mitochondrial genomes (mtGenomes). In forensic genetics (partial) mtGenome information can be used to assign haplotypes to their phylogenetic backgrounds, which may, in turn, have characteristic geographic distributions that would offer useful information in a forensic case. In addition and perhaps even more relevant in the forensic context, haplogroup-specific patterns of mutations form the basis for quality control of mtDNA sequences.