Forensic Population Genetics - Short Communication| Volume 10, e1-e3, May 2014

Population genetics of 17 Y-STR markers in Turkish Cypriots from Cyprus

Published:January 21, 2014DOI:


      We analyzed seventeen Y-chromosomal short tandem repeats (STRs) [DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, Y-GATA-H4, DYS437, DYS438, and DYS448] in 253 unrelated, male individuals from the Turkish Cypriot population of the Eastern Mediterranean island of Cyprus. While 206 out of the 253 haplotypes present in the dataset were unique, there are also 22 haplotypes that were observed in two individuals each, and 1 haplotype that was observed in three individuals. While no locus duplications or null alleles were observed in our dataset, we have detected 43 allelic variants in total, the majority of which (25 out of 253 haplotypes or 9.88%) comprised of .2 intermediate variants at the DYS458 locus (alleles 16.2, 17.2, 18.2, 19.2, and 20.2). For the 229 different haplotypes observed in the Turkish Cypriot dataset, the calculated discrimination capacity (DC) was 0.9051 and the haplotype diversity (HD) was 0.9992. The calculated average gene diversity (GD) values ranged from 0.3828 to 0.9631 for the DYS392 and DYS385a/b loci, respectively. Pairwise genetic distance comparisons of the Turkish Cypriot Y-STR dataset with those from the neighbouring (Turkey, Greece, Israel/Palestinian Authority area, Egypt and Italy) and relatively distant (Lithuania, Taiwan and Australia) countries through the use of analysis of molecular variance (AMOVA) and multi-dimensional scaling (MDS) analyses confirmed that our data do not deviate significantly from the typical core haplotypes of the Eastern Mediterranean region. The Turkish Cypriot Y-STR haplotype dataset will find an immediate use in the Committee on Missing Persons in Cyprus Project on the “Exhumation, Identification and Return of Remains of Missing Persons” and it is also expected to contribute to the establishment of forensic genetic services in North Cyprus.


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      1. The Earliest Prehistory of Cyprus: From Colonization to Exploitation.
        Cyprus American Archaeological Research Institute Monograph Series. Vol. 2. American Schools of Oriental Research Publications, Boston2001
        • Applied Biosystems
        AmpFlSTR® Yfiler TM PCR Amplification Kit User's Manual, Foster City, CA.
        • Gusmao L.
        • Butler J.M.
        • Carracedo A.
        • Gill P.
        • Kayser M.
        • Mayr W.R.
        • Morling N.
        • Prinz M.
        • Roewer L.
        • Tyler-Smith C.
        • Schneider P.M.
        DNA Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis.
        Forensic Sci. Int. 2006; 157: 187-197
        • Willuweit S.
        • Roewer L.
        Y chromosome haplotype reference database (YHRD): update.
        Forensic Sci. Int. Genet. 2007; : 83-87
        • Brisighelli F.
        • Blanco-Verea A.
        • Boschi I.
        • Garaghnani P.
        • Pascali V.L.
        • Carracedo A.
        • Capelli C.
        • Salas A.
        Patterns of Y-STR variation in Italy.
        Forensic Sci. Int. Genet. 2012; 6: 834-839
        • Kovatsi L.
        • Saunier J.L.
        • Irwin J.A.
        Population genetics of Y-chromosome STRS in a population of Northern Greeks.
        Forensic Sci. Int. Genet. 2009; 4: e21-e22
        • Serin A.
        • Canan H.
        • Alper B.
        • Sertdemir Y.
        Haplotype frequencies of 17 Y-chromosomal short tandem repeat loci from the Cukurova region of Turkey.
        Croat. Med. J. 2011; 52: 703-708
        • Ozbas-Gerceker F.
        • Bozman N.
        • Arslan A.
        • Serin A.
        Population data for 17 Y-STRs in samples from Southeastern Anatolia Region of Turkey.
        Int. J. Hum. Genet. 2013; 13: 105-111
        • Triki-Fendri S.
        • Sanchez-Diz P.
        • Rey-Gonzales D.
        • Ayadi I.
        • Alfadhli S.
        • Rebai A.
        • Carracedo A.
        Population genetics of 17-Y-STR markers in West Libya (Tripoli region).
        Forensic Sci. Int. Genet. 2013; 7: e59-e61
        • Ruitberg C.M.
        • Reeder D.J.
        • Butler J.M.
        STRBase: a short tandem repeat DNA database for the human identity testing community.
        Nucleic Acids Res. 2001; 29: 320-322
        • Excoffier L.
        • Lischer H.E.
        Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows.
        Mol. Ecol. Resour. 2010; 10: 564-567
        • Nei M.
        Molecular Evolutionary Genetics.
        Columbia University Press, New York1987: 176-179
        • Cakir A.H.
        • Celebioglu A.
        • Yardimci E.
        Y-STR haplotypes in Central Anatolia region of Turkey.
        Forensic Sci. Int. 2004; 144: 59-64
        • Fernandes A.T.
        • Goncalves R.
        • Gomes S.
        • Filon D.
        • Nebel A.
        • Faerman M.
        • Brehm A.
        Y-chromosomal STRs in two populations from Israel and the Palestinian Authority Area: Christian and Muslim Arabs.
        Forensic Sci. Int. Genet. 2011; 5: 561-562
        • Manni F.
        • Leonardi P.
        • Barakat A.
        • Rouba H.
        • Heyer E.
        • Klintschar M.
        • Mcelreavey K.
        • Quintana-Murci L.
        Y-chromosome analysis in Egypt suggests a genetic regional continuity in Northeastern Africa.
        Hum. Biol. 2002; 74: 645-658
        • Caplinskiene M.
        • Pauliukevicius A.
        • Jankauskiene J.
        • Bunokiene D.
        • Kukiene J.
        • Savanevskyte K.
        • Jureniene A.
        Autosomal and Y-STR mutations in Lithuanian population.
        Forensic Sci. Int. Genet. Suppl. 2008; 1: 237-238
        • Wu F.-C.
        • Ho C.-W.C.-E.P.
        • Hu K.-Y.
        • Willuweit S.
        • Roewer L.
        • Liu D.H.
        Y-chromosomal STRs in the Taiwanese Paiwan population.
        Int. J. Legal Med. 2011; 125: 39-43
        • Taylor D.A.
        • Henry J.M.
        Haplotype data for 16 Y-chromosome STR loci in Aboriginal and Caucasian populations in South Australia.
        Forensic Sci. Int. Genet. 2012; 6: e187-e188
        • Hochberg Y.
        A sharper Bonferroni procedure for multiple tests of significance.
        Biometrika. 1988; 75: 800-802
      2. SPSS Statistics for Windows, version 21, SPSS Inc., Chicago, IL.

        • Carrracedo A.
        • Butler J.M.
        • Gusmao L.
        • Linacre A.
        • Parson W.
        • Roewer L.
        • Schneider P.M.
        New guidelines for the publication of genetic population data.
        Forensic Sci. Int. Genet. 2013; 7: 217-220