Abstract
We analyzed seventeen Y-chromosomal short tandem repeats (STRs) [DYS456, DYS389I,
DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392,
Y-GATA-H4, DYS437, DYS438, and DYS448] in 253 unrelated, male individuals from the
Turkish Cypriot population of the Eastern Mediterranean island of Cyprus. While 206
out of the 253 haplotypes present in the dataset were unique, there are also 22 haplotypes
that were observed in two individuals each, and 1 haplotype that was observed in three
individuals. While no locus duplications or null alleles were observed in our dataset,
we have detected 43 allelic variants in total, the majority of which (25 out of 253
haplotypes or 9.88%) comprised of .2 intermediate variants at the DYS458 locus (alleles
16.2, 17.2, 18.2, 19.2, and 20.2). For the 229 different haplotypes observed in the
Turkish Cypriot dataset, the calculated discrimination capacity (DC) was 0.9051 and
the haplotype diversity (HD) was 0.9992. The calculated average gene diversity (GD)
values ranged from 0.3828 to 0.9631 for the DYS392 and DYS385a/b loci, respectively.
Pairwise genetic distance comparisons of the Turkish Cypriot Y-STR dataset with those
from the neighbouring (Turkey, Greece, Israel/Palestinian Authority area, Egypt and
Italy) and relatively distant (Lithuania, Taiwan and Australia) countries through
the use of analysis of molecular variance (AMOVA) and multi-dimensional scaling (MDS)
analyses confirmed that our data do not deviate significantly from the typical core
haplotypes of the Eastern Mediterranean region. The Turkish Cypriot Y-STR haplotype
dataset will find an immediate use in the Committee on Missing Persons in Cyprus Project
on the “Exhumation, Identification and Return of Remains of Missing Persons” and it
is also expected to contribute to the establishment of forensic genetic services in
North Cyprus.
Keywords
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Article info
Publication history
Published online: January 21, 2014
Accepted:
January 8,
2014
Received in revised form:
January 7,
2014
Received:
October 10,
2013
Footnotes
☆Access to data is available upon request from the corresponding author ([email protected]).
Identification
Copyright
© 2014 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
