Abstract
A set of low template mixed DNA profiles with known ground truths was examined using
software that utilised peak heights (STRmix™ V2.3) and an adapted version that did
not use peak heights and mimicked models based on a drop-out probability [
1
,
2
] (known as semi-continuous or ‘drop’ models) (STRmix™ lite). The use of peak heights
increased the LR when Hp was true in the vast majority of cases. The effect was most notable at moderate template
levels but was also present at quite low template levels. There is no level at which
we can say that height information is totally uninformative. Even at the lowest levels
the bulk of the data show some improvement from the inclusion of peak height information.Keywords
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References
- An investigation of the rigor of interpretation rules for STR's derived from less that 100 pg of DNA.Forensic Sci. Int. 2000; 112: 17-40
- Interpreting low template DNA profiles.Forensic Sci. Int. Genet. 2009; 4: 1-10
- The interpretation of single source and mixed DNA profiles.Forensic Sci. Int. Genet. 2013; 7: 516-528
- An open-source initiative for the evaluation of statistical methods in forensic genetics.Forensic Sci. Int. Genet. 2011; 5: 265-268
- Calculating the weight of evidence in low-template forensic DNA casework.J. Forensic Sci. 2013; 58: 234-259
- Statistical evaluation of forensic DNA profile evidence.Annu. Rev. Stat. Appl. 2014; 1: 1-4
- Evaluating forensic DNA profiles using peak heights, allowing for multiple donors, allelic dropout and stutters.Forensic Sci. Int. Genet. 2013; 7: 555-563
- Validating TrueAllele® DNA mixture interpretation.J. Forensic Sci. 2011; 56: 1430-1447
- Probabilistic modelling for DNA mixture analysis.Forensic Sci. Int. Genet. 2008; 1: 640-642
- Using continuous DNA interpretation methods to revisit likelihood ratio behaviour.Forensic Sci. Int. Genet. 2014; 11: 144-153
- A universal strategy to interpret DNA profiles that does not require a definition of low-copy-number.Forensic Sci. Int. Genet. 2010; 4: 221-227
- Statistical analysis of a large file of STR profiles of British Caucasians to support forensic casework.Int. J. Legal Med. 1996; 109: 173-177
- A new methodological framework to interpret complex DNA profiles using likelihood ratios.Forensic Sci. Int. Genet. 2013; 7: 251-263
- Probability and the Weighing of Evidence.Charles Griffin & Company Limited, London1950
Article info
Publication history
Published online: November 14, 2014
Accepted:
November 5,
2014
Received in revised form:
October 10,
2014
Received:
September 5,
2014
Identification
Copyright
© 2014 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.