A set of low template mixed DNA profiles with known ground truths was examined using software that utilised peak heights (STRmix™ V2.3) and an adapted version that did not use peak heights and mimicked models based on a drop-out probability [
- Gill P.
- Whitaker J.P.
- Flaxman C.
- Brown N.
- Buckleton J.S.
An investigation of the rigor of interpretation rules for STR's derived from less that 100 pg of DNA.
Forensic Sci. Int. 2000; 112: 17-40
2] (known as semi-continuous or ‘drop’ models) (STRmix™ lite). The use of peak heights increased the LR when Hp was true in the vast majority of cases. The effect was most notable at moderate template levels but was also present at quite low template levels. There is no level at which we can say that height information is totally uninformative. Even at the lowest levels the bulk of the data show some improvement from the inclusion of peak height information.
- Balding D.J.
- Buckleton J.
Interpreting low template DNA profiles.
Forensic Sci. Int. Genet. 2009; 4: 1-10
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- An investigation of the rigor of interpretation rules for STR's derived from less that 100 pg of DNA.Forensic Sci. Int. 2000; 112: 17-40
- Interpreting low template DNA profiles.Forensic Sci. Int. Genet. 2009; 4: 1-10
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Published online: November 14, 2014
Accepted: November 5, 2014
Received in revised form: October 10, 2014
Received: September 5, 2014
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