Highlights
- •286 West Africans from five ethnic groups were typed for 17 Y-STRs and 96 Y-SNPs.
- •Statistical analyses show close genetic distances between groups from Ivory Coast and Benin.
- •Significant genetic differentiation was observed between Yoruba groups from Benin and Nigeria.
Abstract
Ninety-six single nucleotide polymorphisms (SNPs) and seventeen short tandem repeat
(STRs) were investigated on the Y-chromosome of 288 unrelated healthy individuals
from populations in Benin (Bariba, Yoruba, and Fon) and the Ivory Coast (Ahizi and
Yacouba). We performed a multidimensional scaling analysis based on FST and RST genetic distances using a large extensive database of sub-Saharan African populations.
There is more genetic homogeneity in Ivory Coast populations compared with populations
from Benin. Notably, the Beninese Yoruba are significantly differentiated from neighbouring
groups, but also from the Yoruba from Nigeria (FST > 0.05; P< 0.01). The Y-chromosome dataset presented here provides new valuable data to understand
the complex genetic diversity and human male demographic events in West Africa.
Keywords
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Article info
Publication history
Published online: August 03, 2015
Accepted:
July 31,
2015
Received in revised form:
July 17,
2015
Received:
April 17,
2015
Identification
Copyright
© 2015 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
