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Research paper| Volume 25, P125-131, November 2016

EMPOP-quality mtDNA control region sequences from Kashmiri of Azad Jammu & Kashmir, Pakistan

  • Allah Rakha
    Correspondence
    Corresponding author at: Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China.
    Affiliations
    Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China

    Department of Forensic Sciences, University of Health Sciences, Lahore, Pakistan
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  • Min-Sheng Peng
    Affiliations
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
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  • Rui Bi
    Affiliations
    Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China
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  • Jiao-Jiao Song
    Affiliations
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
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  • Zeenat Salahudin
    Affiliations
    Department of Forensic Sciences, University of Health Sciences, Lahore, Pakistan
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  • Atif Adan
    Affiliations
    Department of Forensic Sciences, University of Health Sciences, Lahore, Pakistan
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  • Muhammad Israr
    Affiliations
    Department of Forensic Studies, University of Swat, Swat, Pakistan
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  • Yong-Gang Yao
    Affiliations
    Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China
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      Highlights

      • MtDNA control region sequences of 317 Kashmiri individuals from Pakistan.
      • Kashmiri population has a high haplotype diversity but low random match probability.
      • The matrilineal structure of Kashmiri resembles typical South Asian populations.
      • The data are available through EMPOP accession number EMP00679.

      Abstract

      The mitochondrial DNA (mtDNA) control region (nucleotide position 16024-576) sequences were generated through Sanger sequencing method for 317 self-identified Kashmiris from all districts of Azad Jammu & Kashmir Pakistan. The population sample set showed a total of 251 haplotypes, with a relatively high haplotype diversity (0.9977) and a low random match probability (0.54%). The containing matrilineal lineages belonging to three different phylogeographic origins of Western Eurasian (48.9%), South Asian (47.0%) and East Asian (4.1%). The present study was compared to previous data from Pakistan and other worldwide populations (Central Asia, Western Asia, and East & Southeast Asia). The dataset is made available through EMPOP under accession number EMP00679 and will serve as an mtDNA reference database in forensic casework in Pakistan.

      Keywords

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