In March 2017, we published an original research paper in Forensic Science International: Genetics about the use of conditional probabilities in Forensic DNA Phenotyping (FDP) [
[1]
]. We highlighted that the relationship between the predictive values of FDP and the
prevalence of the investigated appearance phenotype depends upon (i) the extent to
which causal factors (genetic and environmental) of the phenotype are accounted for
by the prediction model used, and (ii) the degree of inter-population variability,
if any, of the remaining causal factors. In fact, if all causal factors are accounted
for by the prediction model, then the predictive values would be the same in every
population, irrespective of the prevalence of the phenotype in question.To read this article in full you will need to make a payment
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References
- Likelihood ratio and posterior odds in forensic genetics: two sides of the same coin.Forensic Sci. Int. Genet. 2017; 28: 203-210
- Germany: note limitations of DNA legislation.Nature. 2017; 545: 30
- Wissenschaftlicher und rechtlicher Klärungsbedarf zur geplanten forensischen Anwendung erweiterter DNA-Analysen. Wissenschaftlliche, ethische & soziale Gesichtspunkte der Anwendung neuer Gen-Analysen im polizeilichen Ermittlungsdienst.2017 (Dr Matthias Wienroth, Prof Dr Veronik Lipphardt. https://stsfreiburg.files.wordpress.com/2017/05/berlin_vortrag_ausgearbeitet_final-2-mit-aktuellem.pdf (pages 7–8, Szenario 1))
Article info
Publication history
Published online: November 13, 2017
Accepted:
November 12,
2017
Received in revised form:
November 8,
2017
Received:
September 29,
2017
Identification
Copyright
© 2017 Elsevier B.V. All rights reserved.
