Highlights
- •Genotyped 58 STRs (27 autosomal, 24 Y-STRs and 7 X-STRs) and 94 autosomal SNPs.
- •Samples from the general population of El Salvador (ES, Central America).
- •Used Verogen ForenSeq™ Primer Mix A to generate length and repeat-sequence alleles.
- •Extremely low overall RMP means it can be applied successfully even if many loci fail.
- •Could be used to identify missing people from ES civil war and deceased migrants.
Abstract
We have genotyped the 58 STRs (27 autosomal, 24 Y-STRs and 7 X-STRs) and 94 autosomal
SNPs in Illumina ForenSeq™ Primer Mix A in a sample of 248 men and 143 women from
El Salvador, Central America. Regional division (Centro, Oriente, Occidente) showed
in almost all cases FST values not significantly different from 0, and further analyses were applied only
to the undivided, country-wide population. The overall random match probability (RMP)
decreased from 6.79 × 10−31 in length-based genotypes in the 27 autosomal STRs to 1.47 × 10−34 in repeat-sequence based genotypes. Combining the autosomal loci in this set, RMP
reaches 2.97 × 10−70. In a population genetic analysis, El Salvador showed the lowest FST values with US Hispanics both for autosomal and X-STRs; however, it was much closer
to Native Americans for the latter than for the former, in accordance with the well-known
gender-biased admixture that created most Latin American populations.
Keywords
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Article info
Publication history
Published online: December 01, 2021
Accepted:
November 28,
2021
Received in revised form:
November 26,
2021
Received:
July 22,
2021
Identification
Copyright
© 2021 Elsevier B.V. All rights reserved.
